Fuchs' endothelial dystrophy

Labelled Diagram of the Eye

Labelled diagram of the structure of the retina

Fuchs' endothelial dystrophy is a hereditary ophthalmic condition in which the endothelium of the cornea of the eye fails to function with age, resulting in small whitish deposits of hyalin (a clear glassy material that can result from the degeneration of some types of tissues, including epithelial cells) forming on the inner surface of the cornea.

Initial symptoms of Fuchs' endothelial dystrophy may include blurred vision on awakening, that gradually clears as the day progresses. However, that symptom alone is not enough to indicate Fuchs' endothelial dystrophy - as for all medical concerns, professional advice should be sought if and when any problems arise.


Fuchs' endothelial dystrophy
is generally only seen in older people and may be an intermittent issue initially, often with only one eye affected in the early stages.

If severe, Fuchs' endothelial dystrophy can lead onto bullous keratopathy which involves thickening and swelling of the cornea.


Treatment of Fuchs' endothelial dystrophy varies according to the severity of the case:

  • Mild cases of early-stage Fuchs' endothelial dystrophy may be treated with prescription hypertonic drops.
  • In some cases a therapeutic soft lens (sometimes called a "bandage lens") may be suggested to help ease discomfort.
  • In severe cases, treatment of Fuchs' endothelial dystrophy may involve keratoplasty.


Fuchs' endothelial dystrophy is named after Austrian Ophthalmologist, Ernst Fuchs (1831 - 1930).

More about Ophthalmology:

This section includes short definitions of many diseases, disorders, and conditions of the eyes and visual system.
For definitions of other terms in this category, choose from the list to the left (but note that this is not a complete/exhaustive list).

Other related pages include

For further information see also our pages of books about ophthalmology.

The following books may also be of interest:

The Aging Eye (Harvard Medical School)
MCQ Companion to the Eye (Textbook)
The Secret of Perfect Vision: How You Can Prevent and Reverse Nearsightedness
What Your Doctor May Not Tell You About(TM) Glaucoma: The Essential Treatments and Advances That Could Save Your Sight

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