Thyroid Stimulating Hormone (TSH)

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Thyroid Stimulating Hormone (TSH), also known as thyrotrophin, is a human hormone that is synthesized and secreted by the anterior pituitary gland (an endocrine gland in the human body).

Thyroid Stimulating Hormone is synthesized and stored in the thyrotrophe cells in the anterior lobe of the pituitary gland, which is called the "adenohypophysis". Its main function is to stimulate the thyroid gland to release two of its own hormones into the bloodstream. These two hormones are triiodothyronine (T3) and thyroxine (T4).

Synthesis of thyroid stimulating hormone is controlled by thyrotrophin-releasing hormone. The other factor that regulates the amount of thyroid stimulating hormone present in the body is the negative feedback mechanism involving the influence of the thyroid hormones themselves.

See also: What is a Hormone ?

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