Membrana Limitans Interna

Labelled diagram of the structure of the retina

Labelled Diagram of the Eye

Labelled diagram of the structure of the retina

Labelled Diagram of the Eye

The Membrana Limitans Interna is the first (1st) of the layers forming the retina of the human eye.

Recall that light from outside the human body enters the eye through its main structures of the cornea, aqueous humour, pupil, lens, etc. and is normally focussed onto the retina of the eye.

The retina is composed of several layers which, together, form the "screen" in the eye onto which an image of the area viewed by the eye is formed, and information about that image is segmented into packets of information that are passed to the visual cortex of the brain via the optic nerve.


The membrana limitans interna is the retinal layer located nearest to the centre of the eyeball (and at the bottom left-hand side of the upper-diagram to the right). It is in contact with the hyaloid membrane of the vitreous humour of the eye.

In common with the Membrana Limitans Externa, the membrana limitans interna is formed from the Fibres of Müller. These fibres of Müller (also known as "radiating fibres") form the supporting framework that connects the layers of the retina together and also forms the Membrana Limitans Interna and the Membrana Limitans Externa.

These layers are so named because they form the two limits between which the fibres of Müller are attached. As the fibres of Müller are stretched between these two "limiting layers", they therefore pass through all of the layers in between - which includes all of the "nervous layers" except Jacob's Membrane (layer 9).


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