Date Published: 5 December 2013

Excess fat on the waistline could prevent cancer killing cells from doing their job

Health News from Ireland (Eire)

Recent research conducted in Ireland has revealed that carrying excess fat on the waistline could prevent cancer killing cells from performing their functions effectively.

According to the recent study, which was funded by the Health Research Board (HRB) in Ireland, excess fat located around the waistline can become inflamed in obesity and it has been linked with increased risk of several cancers including oesophageal adenocarcinoma, incidence of which has doubled in the past two decades. There are now approx. 300 new cases in Ireland each year.

" We wanted to investigate why obesity is so closely linked with this particular cancer", said Dr Joanne Lysaght, Assistant Professor at the Department of Surgery, Trinity College Dublin.
" ... and we found some clues in the immune cells that turned up deep in the obese belly fat."

Her team analysed fat samples from 40 patients who underwent surgery for oesophageal adenocarcinoma. The research team found that the fat from obese patients (see also 'what is obesity' and the 'health risks of obesity') contained high levels of active immune cells called T cells, which are a type of lymphocyte.

" We found that about 40% of the T cells were activated and inflammatory, and these are exactly the types of cells you want to kill a cancer tumour. These T cells could be contributing to inflammation, which is generally linked to cancer, or the obese fat could be acting as a sink for these cells meaning they can't do their job and go and fight the tumour. There is still a lot to find out, but these findings will help shed light on how to intervene to help ensure the T cells can do their job in fighting cancer", she explained.

 

 

Source: Health Research Board (Ireland).
http://www.hrb.ie -

Also in the News:

By 2043 obesity might exceed smoking as the largest preventable cause of cancer in women - 25 Sep '18

Positive effects of exercise on blood cell populations - 20 Jun '18

Brits walk less than one mile per day - 25 May '17

European Obesity Day 2017 - 20 May '17

Obesity and alcohol use in Australia - 5 Apr '16

AMA endorses 2015-2020 Dietary Guidelines (USA) - 8 Jan '16

Vet charity warning about pet obesity - 25 Mar '15

Young smokers father fatter sons - 2 Apr '14

Be a secret angel today: How many anonymous good turns can you do in just 24 hours ?

Although care has been taken when compiling this page, the information contained might not be completely up to date. Accuracy cannot be guaranteed. This material is copyright. See terms of use.

IvyRose Holistic 2003-2019.