Date Published: 11 October 2006
Vaccination breakthrough for animals in danger - Glasgow Univ
A new technique for vaccinating large groups of animals has been tested by researchers at the Universities of Glasgow, Edinburgh and Oxford - and the results of their work could have far-reaching implications for species in danger of being wiped out by disease.
The findings of the research led by Dr Dan Haydon from the Institute of Biomedical and Life Sciences, along with Dr Louise Matthews from the Faculty of Veterinary Medicine, will feature on the cover of this week’s Nature magazine.
Rather than vaccinating the majority of a group of animals against disease, as is traditional, they found that by targeting just 30%, the spread of an outbreak could be curtailled.
Dr Haydon said:
Along with representatives from Oxford University and University of Edinburgh, they demonstrated that by vaccinating just thirty per cent of the Ethiopian wolf population – the rarest carnivores in the world – they could reduce the spread of rabies during an outbreak and consequently, the number of animals that die from the disease.
Their study suggests that by vaccinating wolf packs living in the connecting mountain valleys close to the outbreak, they can contain disease outbreaks with unexpectedly low overall levels of vaccine coverage.
The findings may provide a new approach for vaccinating other populations of endangered wild animals.
The population of just 500 Ethiopian wolves can only be found in remote mountain enclaves in the Ethiopian Highlands.
Canid diseases, such as rabies and distemper, are the major killers, with domestic dogs being the main disease-carriers.
After rabies outbreaks in the Bale Mountains in the early 1990s wiped out three quarters of the Ethiopian wolf population in this area, an emergency vaccination programme was introduced in 2003 in response to yet another outbreak that year.
Analysis suggested that a preventative strategy to capture and vaccinate the whole population was impractical as the wolves live in remote, inaccessible mountainous areas.
The alternative strategy is an effective reactive response to outbreaks, whereby Ethiopian wolves living in the mountain valleys close to infected packs are targeted. Such strategies are likely to become cheaper and more easily implemented with the development of protocols for the delivery of currently available oral vaccines.
Professor David Macdonald, Director of the Oxford’s Wildlife Conservation Research Unit, said:
This Glasgow-led study builds on the long association the University has had with many African countries and comes at a time when the University is developing even stronger ties with African academics and scientists through its recently formed Glasgow University Africa Group. This group supports the University’s links with Africa through research, teaching and fund raising.
Source: Glasgow University (Scotland, UK).